DS-8X Eight Channel Spectrophotometer
Why Choose the DS-8X?
DeNovix takes high throughput spectrophotometry to a new level of performance with the DS-8X Eight Channel Spectrophotometer. This easy-to-use, stand-alone device delivers full spectrum UV-Vis analysis, making it ideal for rapid nucleic acid and protein quantification.

The DeNovix Difference: SmartQC™ Sample Assurance
The DS-8X employs a suite of quality assurance features to ensure reliable and accurate microvolume measurements. Proprietary DeNovix SmartPath™ technology uses micron-level pathlength control and immediate absorbance feedback. The measurement pathlength for every sample is automatically optimized through continuous sample compression.
Bridge Testing™ verification eliminates unreliable results that stem from broken sample columns or loading issues. The algorithm detects unbridged samples and adjusts in real-time to deliver accurate results, even for challenging 1 µL protein samples.
Automatically Optimized for Every Sample
Multiple algorithms ensure confidence in results while also providing important information about possible sample anomalies.

GxP Compliance Ready
Optional 21 CFR Part 11 Software
EasyApps Secure provides an optional suite of software controls that allow regulated GxP facilities to easily add DS-8X instruments to their compliant workflows (view the compliance statement). The software is fully integrated within the onboard operating system and includes a range of features essential to ensuring compliance, including:
- Password protected system access
- Integrated electronic signature controls
- Comprehensive user account management
- ure audit trail recording
- Advanced data handling and export tools

Designed by Life Scientists, For Life Scientists
Multi-Mode Flexibility
- Full spectrum UV-Vis: 190 – 840 nm
- Single Sample (2 sec); Up to Eight Samples (~10 sec)
- 1µL UV-Vis, Cuvette, and Fluorescence options
User-Friendly Pipette Guide
Our ergonomic pipette guide ensures error-free sample loading. Adjustable to accommodate for left- or right-handed users and any size pipette tip.
Stand-Alone (No PC)
Easy operation and no additional laptop or PC maintenance thanks to a 7 inch HD touchscreen, compatible with all common laboratory gloves.
LED Sample Tracker
Never lose track of where you are on your plate! This plug and play USB accessory links with the DS-8X to help guide your loading process. Software-controlled LEDs illuminate the correct sample column to measure based on your plate layout.

Software Features:







A Splash of Colour in Your Lab
All DS-Series models are available in four colors: Brazilian Blue, Arctic White, Tungsten Silver, and Fire Red.

Wide Range of Applications
The DS-8X excels in a wide range of applications through the ease of use, wide dynamic range, and contamination detection of UV-Vis. The DS-8X is also compatible with the FX Fluorescence Module to enable the enhanced sensitivity and specificity of fluorescence quantification.






Resources:
Brochures:
Technical Notes:
i) Performance Data
- TN 166 DeNovix DS-11 Series Comparison to Thermo Fisher NanoDrop One Spectrophotometer
- TN 172 DeNovix DS-11 Series Fluorometer vs Thermo Fisher Qubit Fluorometer Comparison
- TN 178 DeNovix SmartQC vs Thermo Fisher NanoDrop Acclaro Technology
- TN 125 DeNovix DS-11 vs Thermo Fisher NanoDrop 2000 Spectrophotometer A Performance Comparison
- TN 105 Microvolume Nucleic Acid Performance Data
- TN 136 DS-11 vs Agilent 8453 Performance Data
- TN 107 Microvolume Protein Performance Data
- TN 108 Microvolume Protein Colorimetric Assay Data
- TN 176 Methods of Protein Quantification
- TN 113 Microvolume Mode Carryover Studies
- TN 115 Microvolume Alexa Fluor 555 Performance Data
- TN 138 Peptide App Performance Data
- TN 168 OD600 Measurements
ii) SmartPath™ Technology:
iii) Fluorescence Performance Data:
-
- TN 200 DeNovix RNA Assay Performance Data
- TN 157 dsDNA Broad Range Assay Performance Data
- TN 158 dsDNA High Sensitivity Assay Performance Data
- TN 159 dsDNA Ultra-High Sensitivity Assay Performance Data
- TN 154 Fluorescence Measurement Best Practices
- TN 156 Absorbance and Fluorescence Quantification
- TN 162 dsDNA Assay Concentration Limits
- TN 169 Thermo Fisher Qubit RNA Assay Performance Data
- TN 171 ssDNA Assay Performance Data
- TN 170 GFP Quantification with DeNovix DS-11 Series
- TN 179 Fluorescein Performance Data
iv) Fluorescence Assay Protocols:
RNA:
- TN 199 DeNovix RNA Assay Short Protocol
- TN 198 DeNovix RNA Assay Protocol
- TN 201 DeNovix RNA Assay Instructions for Thermo Fisher Qubit Fluorometers
dsDNA
- TN 142 Broad Range Assay Standard Protocol
- TN 143 Broad Range Assay Detailed Protocol
- TN 144 High Sensitivity Assay Standard Protocol
- TN 145 High Sensitivity Assay Detailed Protocol
- TN 146 Ultra High Sensitivity Assay Standard Protocol
- TN 147 Ultra High Sensitivity Assay Detailed Protocol
- TN 207 DeNovix dsDNA High Sensitivity Assay Instructions for Thermo Fisher Qubit 30 4 Fluorometers
- TN 208 DeNovix dsDNA Ultra High Sensitivity Assay Instructions for Thermo Fisher Qubit 30 4 Fluorome
v) Best Practices and Troubleshooting:
- TN 180 Five Ways to Improve the Accuracy of 1 µL UV-Vis Quantification
- TN 106 Spectrophotometry Best Practices
- TN 175 Microvolume Reproducibility Tips
- TN 110 Microvolume Sample Surface Cleaning
- TN 130 Purity Ratios Explained
- TN 123 Microvolume Pathlength Verification Protocol
- TN 174 Cuvette Absorbance Verification Protocol
- TN 131 Diagnostics App Self Test
- TN 175 Microvolume Reproducibility Tips
- DS-11-FX+-Series-Troubleshooting-Guide
vi) Software Notes:
NanoDrop™, Acclaro™ and Qubit™ are registered trademarks of Thermo Fisher Scientific and its subsidiaries and are used for identification and references purposes only. DeNovix, DeNovix products and this website are not endorsed by Thermo Fisher Scientific.